Publications

This page summarises articles published in peer reviewed journals, professional magazines, and trade journals produced by the NANOCI project.

Publications (peer reviewed)

  1. NANOCI—Nanotechnology Based Cochlear Implant With Gapless Interface to Auditory Neurons. Pascal Senn, Marta Roccio, Stefan Hahnewald, Claudia Frick, Monika Kwiatkowska, Masaaki Ishikawa, Peter Bako, Hao Li, Fredrik Edin, Wei Liu, Helge Rask-Andersen, Ilmari Pyykkö, Jing Zou, Marika Mannerström, Herbert Keppner, Alexandra Homsy, Edith Laux, Miguel Llera, Jean-Paul Lellouche, Stella Ostrovsky, Ehud Banin, Aharon Gedanken, Nina Perkas, Ute Wank, Karl-Heinz Wiesmüller, Pavel Mistrík, Heval Benav, Carolyn Garnham, Claude Jolly, Filippo Gander, Peter Ulrich, Marcus Müller, and Hubert Löwenheim. Otology & Neurotology. 38, no. 8 (2017): e224-e231. doi: 10.1097/MAO.0000000000001439
  2. Efficient penetration of ceric ammonium nitrate oxidant-stabilized gamma-maghemite nanoparticles through the oval and round windows into the rat inner ear as demonstrated by MRI. Jing Zou, Stella Ostrovsky, Liron L. Israel, Hao Feng, Mikko I. Kettunen, Jean-paul Moshe Lellouche, and Ilmari Pyykkö. Journal of Biomedical Materials Research Part B: Applied Biomaterials. (2016). doi: 10.1002/jbm.b.33719
  3. Liquid-air based Fabry-Pérot cavity on fiber tip sensor. Miguel Llera, Thierry Aellen, Javier Hervas, Yves Salvadé, Pascal Senn, Sébastien Le Floch, and Herbert Keppner. Optics Express. 24, no. 8 (2016): 8054. doi: 10.1364/OE.24.008054
  4. Two are Better than One: Combining ZnO and MgF2Nanoparticles ReducesStreptococcus pneumoniaeandStaphylococcus aureusBiofilm Formation on Cochlear Implants. Michal Natan, Fredrik Edin, Nina Perkas, Gila Yacobi, Ilana Perelshtein, Elad Segal, Alexandra Homsy, Edith Laux, Herbert Keppner, Helge Rask-Andersen, Aharon Gedanken, and Ehud Banin. Advanced Functional Materials. 26, no. 15 (2016): 2473-2481. doi: 10.1002/adfm.201504525
  5. Guided growth of auditory neurons: Bioactive particles towards gapless neural – electrode interface. Hao Li, Fredrik Edin, Hisamitsu Hayashi, Olafur Gudjonsson, Niklas Danckwardt-Lillieström, Håkan Engqvist, Helge Rask-Andersen, and Wei Xia. Biomaterials. 122 (2017): 1-9. doi: 10.1016/j.biomaterials.2016.12.020
  6. The effect of pulsed electric fields on the electrotactic migration of human neural progenitor cells through the involvement of intracellular calcium signaling. Hisamitsu Hayashi, Fredrik Edin, Hao Li, Wei Liu, and Helge Rask-Andersen. Brain Research. 1652 (2016): 195-203. doi: 10.1016/j.brainres.2016.09.043
  7. Biofunctionalized peptide-based hydrogels provide permissive scaffolds to attract neurite outgrowth from spiral ganglion neurons. Claudia Frick, Marcus Müller, Ute Wank, Anke Tropitzsch, Benedikt Kramer, Pascal Senn, Helge Rask-Andersen, Karl-Heinz Wiesmüller, and Hubert Löwenheim. Colloids and Surfaces B: Biointerfaces. 149 (2017): 105-114. doi: 10.1016/j.colsurfb.2016.10.003
  8. Spiral Ganglion Neuron Explant Culture and Electrophysiology on Multi Electrode Arrays. Stefan Hahnewald, Marta Roccio, Anne Tscherter, Jürg Streit, Ranjeeta Ambett, and Pascal Senn. Journal of Visualized Experiments. , no. 116 (2016). doi: doi:10.3791/54538
  9. Conductive hybrid carbon nanotube (CNT)–polythiophene coatings for innovative auditory neuron-multi-electrode array interfacing. S. Ostrovsky, S. Hahnewald, R. Kiran, P. Mistrik, R. Hessler, A. Tscherter, P. Senn, J. Kang, J. Kim, M. Roccio, and J. P. Lellouche. RSC Adv. 6, no. 48 (2016): 41714-41723. doi: 10.1039/c5ra27642j
  10. Cell cycle reactivation of cochlear progenitor cells in neonatal FUCCI mice by a GSK3 small molecule inhibitor. M. Roccio, S. Hahnewald, M. Perny, and P. Senn. Scientific Reports. 5, no. 1 (2015). doi: 10.1038/srep17886
  11. Response profiles of murine spiral ganglion neurons on multi-electrode arrays. Stefan Hahnewald, Anne Tscherter, Emanuele Marconi, Jürg Streit, Hans Rudolf Widmer, Carolyn Garnham, Heval Benav, Marcus Mueller, Hubert Löwenheim, Marta Roccio, and Pascal Senn. J Neural Eng. 13, no. 1 (2015): 016011. doi: 10.1088/1741-2560/13/1/016011
  12. Targeted Delivery of Contrast Agents to the Tympanic Medial Wall at Minimum Amount and the Efficient Uptake in the Inner Ear through Oval and Round Windows. Zou J, Ostrovsky S, Israel LL, Lellouche JP and Pyykkö I. Austin J Radiol. 2015; 2(6): 1034. Open access
  13. Calcium Metabolism Profile in Rat Inner Ear Indicated by MRI after Tympanic Medial Wall Administration of Manganese Chloride. Jing Zou, Ilmari Pyykkö. Ann Otol Rhinol Laryngol. Posted online before print on July 29, 2015. doi:10.1177/0003489415597916
  14. Methyl methacrylate embedding to study the morphology and immunohistochemistry of adult guinea pig and mouse cochleae. Peter Bako, Mohamed Bassiouni, Andreas Eckhard, Imre Gerlinger, Claudia Frick, Hubert Löwenheim, Marcus Müller. Cell Tissue Res. 254, 86–93, 2015. doi:10.1016/j.jneumeth.2015.07.017
  15. Molecular organization and fine structure of the human tectorial membrane: is it replenished? Hayashi H, Schrott-Fischer A, Glueckert R, Liu W, Salvenmoser W, Santi P, Rask-Andersen H. Cell Tissue Res. 362( 3), pp 513-527, 2015. doi:10.1007/s00441-015-2225-5
  16. Fine control of drug delivery for cochlear implant applications. Alexandra Homsy, Edith Laux, Julien Brossard, Harry J. Whitlow, Marta Roccio, Stefan Hahnewald, Pascal Senn, Pavel Mistrík, Roland Hessler, Teresa Melchionna, Claudia Frick, Hubert Löwenheim, Marcus Müller, Ute Wank, Karl-Heinz Wiesmüller, and Herbert Keppner. Hearing, Balance and Communication. 15 (4) 153-159, 2015. doi:10.3109/21695717.2015.1048082
  17. Auditory Nerve Preservation and Regeneration in Man - Relevance for Cochlear Implantation. Helge Rask-Andersen and Wei Li. Neural Regeneration Research, 10(5), 710-712–65, 2015. doi:10.4103/1673-5374.156963
  18. X-ray microtomographic confirmation of the reliability of CBCT in identifying the scalar location of cochlear implant electrode after round window insertion. Zou J, Hannula M, Lehto K, Feng H, Lähelmä J, Aula AS, Hyttinen J, Pyykkö I. Hearing Research, 326, 59–65, 2015. doi:10.1016/j.heares.2015.04.005
  19. Solid on liquid deposition, a review of technological solutions. Alexandra Homsy, Edith Laux, Laure Jeandupeux, Jerome Charmet, Roland Bitterli, Chiara Botta, Yves Rebetez, Oksana Banakh, H. Keppner. Microelectronic Engineering, 141, 267–79, 2015. doi:10.1016/j.mee.2015.03.068
  20. Imaging cochlear implantation with round window insertion in human temporal bones and cochlear morphological variation using high-resolution cone beam CT. Zou J, Lähelmä J, Koivisto J, Dhanasingh A, Jolly C, Aarnisalo A, Wolff J, Pyykkö I. Acta Otolaryngol. 135(5), 466-472, 2015. doi:10.3109/00016489.2014.993090
  21. Macromolecular organization and fine structure of the human basilar membrane - RELEVANCE for cochlear implantation. Wei Liu, Francesca Atturo, Robair Aldaya, Peter Santi, Sebahattin Cureoglu, Sabrina Obwegeser, Rudolf Glueckert, Kristian Pfaller, Annelies Schrott-Fischer and Helge Rask-Andersen. Cell Tissue Res. 360(2), 245–262, 2015. doi:10.1007/s00441-014-2098-z
  22. Imaging Optimization of Temporal Bones With Cochlear Implant Using a High-resolution Cone Beam CT and the Corresponding Effective Dose. Jing Zou, Juha Koivisto, Jaakko Lähelmä, Antti Aarnisalo, Jan Wolff, and Ilmari Pyykkö. Ann Otol Rhinol Laryngol 124(6) 466-473, 2015. doi:10.1177/0003489414565004
  23. MeV ion beam lithography of biocompatible halogenated Parylenes using aperture masks. Harry J. Whitlow, Rattanaporn Norarat, Marta Roccio, Patrick Jeanneret, Edouard Guibert, Maxime Bergamin, Gianni Fiorucci, Alexandra Homsy, Edith Laux, Herbert Keppner, Pascal Senn. Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms. 354, 34–36, 2015. doi:10.1016/j.nimb.2014.10.024
  24. The pre- and post-somatic segments of the human type I spiral ganglion neurons – Structural and functional considerations related to cochlear implantation. W. Liu, F. Edin, F. Atturo, G. Rieger, H. Löwenheim, P. Senn, M. Blumer, A. Schrott-Fischer, H. Rask-Andersen, R. Glueckert. Neuroscience, 284, 470-482, 2015. doi:10.1016/j.neuroscience.2014.09.059
  25. 3-D gel culture and time-lapse video microscopy of the human vestibular nerve. Fredrik Edin, Wei Liu, Hao Li, Francesca Atturo, Peetra U. Magnusson, Helge Rask-Andersen. Acta Oto-Laryngologica, 134(12), 1211-1218, 2014. doi:10.3109/00016489.2014.946536 | Open access repository
  26. Differentiation of human neural progenitor cell-derived spiral ganglion-like neurons: a time-lapse video study. Fredrik Edin, Wei Liu, Marja Boström, Peetra U. Magnusson, Helge Rask-Andersen. Acta Oto-Laryngologica, 134(5), 441-447, 2014. doi:10.3109/00016489.2013.875220
  27. Immunohistological analysis of neurturin and its receptors in human cochlea. Wei Liu, Helge Rask-Andersen. Auris Nasus Larynx, 41(2), 172-178, 2014. doi:10.1016/j.anl.2013.07.016
  28. Possible role of gap junction intercellular channels and connexin 43 in satellite glial cells (SGCs) for preservation of human spiral ganglion neurons. Wei Liu, Rudolf Glueckert, Fred H. Linthicum, Gunde Rieger, Michael Blumer, Mario Bitsche, Elisabeth Pechriggl, Helge Rask-Andersen, Annelies Schrott-Fischer. Cell and Tissue Research, 355(2), 267-278, 2014. doi:10.1007/s00441-013-1735-2
  29. Nanoparticle based inner ear therapy. Ilmari Pyykkö. World Journal of Otorhinolaryngology, 3(4), 114-133, 2013. doi:10.5319/wjo.v3.i4.114
  30. Distribution of pejvakin in human spiral ganglion: An immunohistochemical study. Wei Liu, Anders Kinnefors, Marja Boström, Fredrik Edin, Helge Rask-Andersen. Cochlear Implants International, 14(4), 225-231, 2013. doi:10.1179/1754762812Y.0000000027

Book chapters

  1. Focal Drug Delivery in Inner Ear Therapy：Focal Controlled Drug Delivery. Springer, London, UK. ISBN: 978-1-4614-9433-1 (Print) 978-1-4614-9434-8 (Online), 2014. Link to publisher.

Professional magazines and trade journals

  1. The clarity of sound. Pan European Networks: Science and Technology 13, Dec 2014. Link
  2. EU-Projekt NANOCI. Mehr Hörqualität für CI-Träger. Audio Infos. 162, 1-5, October 2014.
  3. Vom Glück der Hörnervenzellen. Fachzeitschrift Schnecke 84(6), 42, 2014. Link
  4. Eine faszinierende Gehörforschung. Hörakustik, 5, 96-97, 2014.
  5. Bald bessere Ohrimplantate durch Nanoci-Forschungsprojekt? dezibel 2, 11-12, 2014. Link
  6. Bessere Ohrenimplantate für Gehörlose. Unilink, die Nachrichten der Universität Bern, 12, 16-17, 2013. Link
  7. «Natürliches» Hören ist das Ziel.» Mit Stammzellen Cochlea-Implantate verbessern - Medical Tribune, 5(1), 6, 2013.